Though the consequences of hormone replacement therapy (HRT) on CVD are favourable, these depend on the girl’s age and medical background.
There’s a trend that HRT is cardioprotective in younger women. In older ladies, there’s a trend to an increase in CVD risk, though this impact is not statistically significant.
Generally, HRT is safe for many younger women (i.e. women going through the or in the first postmenopausal period) for the relief of menopausal symptoms.
Girls older than 60 years, or those with predisposing risk factors, have a very slightly increased CVD risk and should be more cautious.
HRT is additionally known slightly to extend the danger of venous thromboembolism.
However, these risks are little and should not deter women consulting their clinician about whether or not HRT is appropriate for them. It’s vital that all women discuss their medical history with their clinician before deciding to take HRT.
"As regards HRT, round the time of the menopause , it’s a small beneficial effect on the cardiovascular system. If you’re taking HRT 10 years after the menopause, it seems to have a negative impact on the cardiovascular system, but it’s necessary to notice, when re-analysing its data this negative result is of marginal significance," said Professor Peter Collins, Professor of Clinical Cardiology at the UK’s National Heart and Lung Institute, Imperial College and Royal Brompton Hospital and Chair of the European Society of Cardiology’s Task Force on Gender.